在墨西哥的丛林深处的神庙，考古学家们发现了一种古老的蛇崇拜文化，同时他们不小心释放了一条沉睡了几个世纪的巨大而可怕的蟒蛇。
Fleeing her past, a troubled hiker and her dog traverse the Appalachian Trail, only to fall under the spell of a dangerous man. As obsession and visions mount, she's drawn toward Mile 666, where lust, death, and something ancient await.
